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Appalachian Center Events

Analysis and PDE Seminar

Title:  On the ground state of the magnetic Laplacian in corner domains

Abstract:  I will present recent results about the first eigenvalue of the magnetic Laplacian in general 3D-corner domains with Neumann boundary condition in the semi-classical limit.  The use of singular chains show that the asymptotics of the first eigenvalue is governed by a hierarchy of model problems on the tangent cones of the domain. We provide estimations of the remainder depending on the geometry and the variations of the magnetic field. This is a joint work with V. Bonnaillie-Nol and M. Dauge.

 

 

Date:
-
Location:
745 Patterson Office Tower

Analysis and PDE Seminar

Title:  On the ground state of the magnetic Laplacian in corner domains

Abstract:  I will present recent results about the first eigenvalue of the magnetic Laplacian in general 3D-corner domains with Neumann boundary condition in the semi-classical limit.  The use of singular chains show that the asymptotics of the first eigenvalue is governed by a hierarchy of model problems on the tangent cones of the domain. We provide estimations of the remainder depending on the geometry and the variations of the magnetic field. This is a joint work with V. Bonnaillie-Nol and M. Dauge.

 

 

Date:
-
Location:
745 Patterson Office Tower

DOPE 2014 Scholar/Activist Panel: Working Across Borders: US/Latin America Collaborations for Social and Environmental Justice

Featuring: Simón Sedillo (organizer and filmmaker); Geoff Boyce (Doctoral Candidate, School of Geography and Development, University of Arizona); Aviva Chomsky (Department of History, Salem State University); Vanessa Hall (Kentuckians for the Commonwealth); and Ann Kingsolver, (Department of Anthropology and Appalachian Studies Center, University of Kentucky)

Date:
-
Location:
Student Center Room 230

Analysis and PDE Seminar

Title: Informatics and Modeling Platform for Stable Isotope-Resolve Metabolomics



Abstract: Recent advances in stable isotope-resolved metabolomics (SIRM) are enabling orders-of-magnitude increase in the number of observable metabolic traits (a metabolic phenotype) for a given organism or community of organisms.  Analytical experiments that take only a few minutes to perform can detect stable isotope-labeled variants of thousands of metabolites.  Thus, unique metabolic phenotypes may be observable for almost all significant biological states, biological processes, and perturbations.  Currently, the major bottleneck is the lack of data analysis that can properly organize and interpret this mountain of phenotypic data as highly insightful biochemical and biological information for a wide range of biological research applications.  To address this limitation, we are developing bioinformatic, biostatistical, and systems biochemical tools, implemented in an integrated data analysis platform, that will directly model metabolic networks as complex inverse problems that are optimized and verified by experimental metabolomics data.  This integrated data analysis platform will enable a broad application of SIRM from the discovery of specific metabolic phenotypes representing biological states of interest to a mechanism-based understanding of a wide range of biological processes with particular metabolic phenotypes.

Date:
-
Location:
745 Patterson Office Tower

Analysis and PDE Seminar

Title: Informatics and Modeling Platform for Stable Isotope-Resolve Metabolomics



Abstract: Recent advances in stable isotope-resolved metabolomics (SIRM) are enabling orders-of-magnitude increase in the number of observable metabolic traits (a metabolic phenotype) for a given organism or community of organisms.  Analytical experiments that take only a few minutes to perform can detect stable isotope-labeled variants of thousands of metabolites.  Thus, unique metabolic phenotypes may be observable for almost all significant biological states, biological processes, and perturbations.  Currently, the major bottleneck is the lack of data analysis that can properly organize and interpret this mountain of phenotypic data as highly insightful biochemical and biological information for a wide range of biological research applications.  To address this limitation, we are developing bioinformatic, biostatistical, and systems biochemical tools, implemented in an integrated data analysis platform, that will directly model metabolic networks as complex inverse problems that are optimized and verified by experimental metabolomics data.  This integrated data analysis platform will enable a broad application of SIRM from the discovery of specific metabolic phenotypes representing biological states of interest to a mechanism-based understanding of a wide range of biological processes with particular metabolic phenotypes.

Date:
-
Location:
745 Patterson Office Tower

Analysis and PDE Seminar

Title:  Smoothness of isometries between subRiemannian manifolds

Abstract:  In a joint work with Enrico Le Donne (Jyvaskyla, Finland), we show that the group of isometries (i.e., distance-preserving homeomorphisms) of an equiregular subRiemannian manifold is a finite-dimensional Lie group of smooth transformations. The proof is based on a new PDE argument, in the spirit of harmonic coordinates, establishing that in an arbitrary subRiemannian manifold there exists an open dense subset where all isometries are smooth.

Date:
-
Location:
215 White Hall Classroom Building

Analysis and PDE Seminar

Title:  Higher-order analogues of the exterior derivative complex

Abstract:  I will discuss some earlier joint work with E. M. Stein concerning div-curl type inequalities for the exterior derivative operator and its adjoint in Euclidean space R^n. I will then present various higher-order generalizations of the notion of exterior derivative, and discuss some recent div-curl type estimates for such operators. Part of this work is joint with A. Raich.

Date:
-
Location:
745 Patterson Office Tower

Analysis and PDE Seminar

Title:  Higher-order analogues of the exterior derivative complex

Abstract:  I will discuss some earlier joint work with E. M. Stein concerning div-curl type inequalities for the exterior derivative operator and its adjoint in Euclidean space R^n. I will then present various higher-order generalizations of the notion of exterior derivative, and discuss some recent div-curl type estimates for such operators. Part of this work is joint with A. Raich.

Date:
-
Location:
745 Patterson Office Tower